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Anti-Infective Agents
Anti-Infective Agents in Medicinal Chemistry
ISSN (Print): 2211-3525
ISSN (Online): 2211-3533
VOLUME: 12
ISSUE: 1
DOI: 10.2174/22113525113119990118









Mini-Review: Polyamines Metabolism, Toxicity and Potent Therapeutical Use

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Author(s): Lamia Djouhri-Bouktab, Jean M. Rolain and Jean M. Brunel
Pages 95-103 (9)
Abstract:
In recent years, extensive researches have emphasized the fact that polyamines conjugates acting as possessing antitumor, antimicrobial candidates are becoming important in the biogical and medicinal field. In this review, a general design strategy of polyamine conjugates as well as recent progress in both fundamental mechanism studies and potent therapeutic use as anti infectious agents are provided for the readers.
Keywords:
Anticancer activity, antimicrobial activity, metabolism, polyamines, therapeutical use.
Affiliation:
Centre de Recherche en Cancérologie de Marseille (CRCM), CNRS, UMR7258; Institut Paoli Calmettes; Aix-Marseille Université, UM 105; Inserm, U1068, F-13009, Marseille, France.