Abstract
The present study was intended to reveal the antibacterial activity of various cold organic solvent extracts of Abrus precatorius L. (Fabaceae) and Asystasia gangetica (L.) T. Anderson (Acanthaceae) against the selected pathogens. Powders of whole plant parts of A. precatorius and A. gangetica were extracted with petroleum ether, benzene, chloroform and ethanol at ambient temperature. The dried extracts were tested for antibacterial activity by agar disc diffusion method. Among the different extracts of A. precatorius, ethanolic extracts showed maximum zone of inhibition (21 mm) against Bacillus subtilis followed by 13 mm against Staphylococcus aureus. Broadest spectrum of activity was exhibited in petroleum ether extracts of A. precatorius against different bacterial pathogens (5/7 pathogens). In A. gangetica, benzene extracts exhibited broadest spectrum of activity with the maximum level of inhibition (12 mm) against B. subtilis followed by 11 mm in ethanolic extracts against Salmonella typhi. Petroleum ether extracts of A. gangetica did not show any activity against the selected pathogens. The present study results clearly show that the extracts of A. precatorius and A. gangetica had significant and considerable antibacterial activity against various pathogens and further evaluation is necessary to find out the active principle compound responsible for bioactivity.
Keywords: Abrus precatorius, antibacterial, Asystasia gangetica, bioactivity, pathogens.
Anti-Infective Agents
Title:Antibacterial Efficacy of Abrus precatorius L. and Asystasia gangetica (L.) T. Anderson
Volume: 12 Issue: 2
Author(s): N. Janakiraman, J. Jasmin Jansi, M. Johnson, M.I. Zahir Hussain and S. Jeeva
Affiliation:
Keywords: Abrus precatorius, antibacterial, Asystasia gangetica, bioactivity, pathogens.
Abstract: The present study was intended to reveal the antibacterial activity of various cold organic solvent extracts of Abrus precatorius L. (Fabaceae) and Asystasia gangetica (L.) T. Anderson (Acanthaceae) against the selected pathogens. Powders of whole plant parts of A. precatorius and A. gangetica were extracted with petroleum ether, benzene, chloroform and ethanol at ambient temperature. The dried extracts were tested for antibacterial activity by agar disc diffusion method. Among the different extracts of A. precatorius, ethanolic extracts showed maximum zone of inhibition (21 mm) against Bacillus subtilis followed by 13 mm against Staphylococcus aureus. Broadest spectrum of activity was exhibited in petroleum ether extracts of A. precatorius against different bacterial pathogens (5/7 pathogens). In A. gangetica, benzene extracts exhibited broadest spectrum of activity with the maximum level of inhibition (12 mm) against B. subtilis followed by 11 mm in ethanolic extracts against Salmonella typhi. Petroleum ether extracts of A. gangetica did not show any activity against the selected pathogens. The present study results clearly show that the extracts of A. precatorius and A. gangetica had significant and considerable antibacterial activity against various pathogens and further evaluation is necessary to find out the active principle compound responsible for bioactivity.
Export Options
About this article
Cite this article as:
Janakiraman N., Jansi Jasmin J., Johnson M., Hussain Zahir M.I. and Jeeva S., Antibacterial Efficacy of Abrus precatorius L. and Asystasia gangetica (L.) T. Anderson, Anti-Infective Agents 2014; 12 (2) . https://dx.doi.org/10.2174/22113525113119990004
DOI https://dx.doi.org/10.2174/22113525113119990004 |
Print ISSN 2211-3525 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-3533 |
Call for Papers in Thematic Issues
An Overview of Drugs for Multiple Targets and Variants of SARS-CoV-2 Through Artificial Intelligence, Machine Learning, Deep Learning, and Experimental Analysis
The emergence and rapid evolution of SARS-CoV-2 variants have posed significant challenges in the ongoing fight against the COVID-19 pandemic. The development of effective treatments for multiple viral targets and variants demands innovative approaches, including artificial intelligence (AI), machine learning (ML), and deep learning (DL) techniques. This special issue aims ...read more
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Blood Cell Count Indexes of Systemic Inflammation in Carotid Artery Disease: Current Evidence and Future Perspectives
Current Pharmaceutical Design Computer based Classification of MR Scans in First Time Applicant Alzheimer Patients
Current Alzheimer Research Novel Insights into the Molecular Mechanisms Involved in the Neuroprotective Effects of C-Phycocyanin against Brain Ischemia in Rats
Current Pharmaceutical Design Pivotal Pathogenic and Biomarker Role of Chlamydia Pneumoniae in Neurovascular Diseases
Current Neurovascular Research Assessing Medication Problems in those ≥ 65 Using the STOPP and START Criteria
Current Aging Science Recent Developments in Catecholic Polymers: Polymerization and Applications
Current Materials Science Critical Review of the Ankle Brachial Index
Current Cardiology Reviews MMP-2 Selectivity in Hydroxamate-Type Inhibitors
Current Medicinal Chemistry Histone Deacetylase (HDAC) Inhibitors as Potential Drugs to Target Memory and Adult Hippocampal Neurogenesis
Current Psychopharmacology The Impact of Asymmetric Dimethylarginine (ADAMA), the Endogenous Nitric Oxide (NO) Synthase Inhibitor, to the Pathogenesis of Gastric Mucosal Damage
Current Pharmaceutical Design Meet Our Editor
Current Clinical Pharmacology Implication of Nanofibers in Oral Drug Delivery
Current Pharmaceutical Design NOS Inhibitors: Structure, Biological Activity and Mechanism of Action
Current Enzyme Inhibition Role of Reactive Oxygen Species in Tumor Necrosis Factor-alpha Induced Endothelial Dysfunction
Current Hypertension Reviews An Update on the Association of Protein Kinases with Cardiovascular Diseases
Current Pharmaceutical Design Inflammation in Cardiovascular Disease and Regulation of the Actin Cytoskeleton in Inflammatory Cells: The Actin Cytoskeleton as a Target
Cardiovascular & Hematological Agents in Medicinal Chemistry Anaemia, Polycythaemia and Chronic Heart Failure
Current Cardiology Reviews Hydrogen Sulfide and Endothelial Dysfunction: Relationship with Nitric Oxide
Current Medicinal Chemistry Meet the Editorial Board:
Current Drug Targets Prevention and Treatment of Coronary Distal Embolization in the Setting of Acute Myocardial Infarction: Pharmacologic Approach
Current Vascular Pharmacology