Abstract
Objective: To study the role of serum Monoamine oxidase (MAO) in Lichen planus(LP). Methods: 82 cases of Lichen planus patients and 35 healthy controls were selected in the investigation. The total serum MAO levels were measured. Results: The levels of serum MAO in Lichen planus patients were significantly higher than those in healthy controls (P<0.01). The severity of Lichen planus was not correlated with serum MAO levels (r =0.4873, t=0.73, p>0.05). Conclusion: According to the findings, there might be a coincidence of MAO and lichen planus. However, further studies are required to clarify the immunological mechanisms which are responsible for MAO synthesis during immunoreaction.
Keywords: Lichen planus, measurement, mechanism, monoamine oxidase, serum.
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry
Title:Measurement of Serum Monoamine Oxidase in Lichen Planus Patients and Its Clinical Significance
Volume: 13 Issue: 1
Author(s): Jianguo Huang, Qiying Gong and Guiming Li
Affiliation:
Keywords: Lichen planus, measurement, mechanism, monoamine oxidase, serum.
Abstract: Objective: To study the role of serum Monoamine oxidase (MAO) in Lichen planus(LP). Methods: 82 cases of Lichen planus patients and 35 healthy controls were selected in the investigation. The total serum MAO levels were measured. Results: The levels of serum MAO in Lichen planus patients were significantly higher than those in healthy controls (P<0.01). The severity of Lichen planus was not correlated with serum MAO levels (r =0.4873, t=0.73, p>0.05). Conclusion: According to the findings, there might be a coincidence of MAO and lichen planus. However, further studies are required to clarify the immunological mechanisms which are responsible for MAO synthesis during immunoreaction.
Export Options
About this article
Cite this article as:
Huang Jianguo, Gong Qiying and Li Guiming, Measurement of Serum Monoamine Oxidase in Lichen Planus Patients and Its Clinical Significance, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2014; 13 (1) . https://dx.doi.org/10.2174/18715230113129990017
DOI https://dx.doi.org/10.2174/18715230113129990017 |
Print ISSN 1871-5230 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-614X |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Orai1 and Transient Receptor Potential Channels as Novel Molecular Targets to Impair Tumor Neovascularization in Renal Cell Carcinoma and other Malignancies
Anti-Cancer Agents in Medicinal Chemistry Editorial [ Hot topic:Updates on Therapeutic Approaches to Inflammatory Skin Diseases: From Molecular Targets to Drug Development. Part I (Guest Editors: L. Korkina & S. Pastore) ]
Current Drug Metabolism Anticancer Antifolates: Current Status and Future Directions
Current Pharmaceutical Design Pharmacological Activation of Protein Phosphatase 2 A (PP2A): A Novel Strategy to Fight Against Human Malignancies?
Current Medicinal Chemistry Evaluation of Interactions Between Platinum-/Ruthenium-Based Anticancer Agents and Human Serum Albumin: Development of HSA Carrier for Metal-Based Drugs
Current Pharmaceutical Design Clinical Impact of Gene Expression Profiling on Oncology Diagnosis, Prognosis, and Treatment
Combinatorial Chemistry & High Throughput Screening Pathways Related to the Anti-Cancer Effects of Metabolites Derived from Cerrado Biome Native Plants: An Update and Bioinformatics Analysis on Oral Squamous Cell Carcinoma
Protein & Peptide Letters TNF-Related Apoptosis-Inducing Ligand (TRAIL) as a Pro-Apoptotic Signal Transducer with Cancer Therapeutic Potential
Current Pharmaceutical Design Risk Factors for the Pap Test Cytological Changes in Iran: A Multicenter Case-Control Study
Current Women`s Health Reviews A Review of Surgical Options to Preserve Fertility in the Treatment of Early Cervical Cancer
Current Women`s Health Reviews Heparanase Inhibitors Facilitate the Assembly of the Basement Membrane in Artificial Skin
Current Tissue Engineering (Discontinued) Vitamin D Receptor Signaling and Pancreatic Cancer Cell EMT
Current Pharmaceutical Design RAS/RAF/MEK Inhibitors in Oncology
Current Medicinal Chemistry Anti-Tuberculosis Drug Induced Hepatotoxicity and Genetic Polymorphisms in Drug-metabolizing Genes
Current Pharmacogenomics Epigenetic Effects of Cadmium in Cancer: Focus on Melanoma
Current Genomics Extraction and Detection Techniques for PAHs Determination in Beverages: A Review
Current Chromatography Ectopic Thyroid Gland: Description of a Case and Review of the Literature
Endocrine, Metabolic & Immune Disorders - Drug Targets Diverse Roles of GADD45α in Stress Signaling
Current Protein & Peptide Science Looking for New Inhibitors for the Epidermal Growth Factor Receptor
Current Topics in Medicinal Chemistry Hypoxia Signaling and the Metastatic Phenotype
Current Molecular Medicine