An Efficient and Environmentally Benign Access Towards Synthesis of Novel 1,2,3-Triazolyl-pyrazoline Hybrids

Title:An Efficient and Environmentally Benign Access Towards Synthesis of Novel 1,2,3-Triazolyl-pyrazoline Hybrids

Volume: 11 Issue: 6

Author(s): Poovan Shanmugavelan, Sangaraiah Nagarajan, Murugan Sathishkumar, Raja Ranganathan and Alagusundaram Ponnuswamy

Affiliation:

Keywords: Efficient, environmentally benign, 1, 2, 3-triazolyl chalcones, 1, 2, 3-triazolyl pyrazoline hybrids, water mediated.

Abstract: An efficient and facile synthesis of a library of hitherto novel 1,2,3-triazolyl-pyrazoline hybrids in water medium has been achieved in excellent yields from easily accessible 1,2,3-triazole linked chalcone precursors. Herein, its noteworthy that the yield of 1,2,3-triazolyl-pyrazoline hybrids in water medium is as good as in commonly used organic solvent for pyrazoline synthesis viz. ethanol. Present protocol involving mild reaction condition, excellent yield and simple reaction procedure was found to be the best synthetic strategy for 1,2,3-triazolyl-pyrazoline hybrids in view of environmentally benign consciousness.

Cite this article as:

Shanmugavelan Poovan, Nagarajan Sangaraiah, Sathishkumar Murugan, Ranganathan Raja and Ponnuswamy Alagusundaram, An Efficient and Environmentally Benign Access Towards Synthesis of Novel 1,2,3-Triazolyl-pyrazoline Hybrids, Letters in Organic Chemistry 2014; 11 (6) . https://dx.doi.org/10.2174/15701786113109990050