Small Molecule PET-Radiopharmaceuticals
Philip H. Elsinga and Rudi A.J.O. Dierckx
Pages 2268-2274 (7)
This review describes several aspects required for the development of small molecule PET-tracers. Design and selection criteria
are important to consider before starting to develop novel PET-tracers. Principles and latest trends in 11C and 18F-radiochemistry are
summarized. In addition an update of some new developments in regulatory aspects is supplied.
PET, small molecules, radiochemistry, preclinical evaluation, carbon-11, fluorine-18.
University Medical Center Groningen, University of Groningen, the Netherlands and Ghent University, Belgium.