Abstract
The current work discussed the criteria that control the non-enzymatic and enzymatic antioxidant activity from a chemical point of view. Two tunable strategies were classified to emphasize the reactivity of non-enzymatic one from the thermodynamic and kinetic perspectives. On the other hand, the non-covalent interactions and the intermediacy of reactive compounds formation were found to be the most efficient tools to modulate the activity of enzymatic antioxidant. Furthermore, the light has been shed on the pro-oxidant behavior of some antioxidants.
Keywords: 2c-3e interaction, antioxidant activity, GPx activity, -stacking, PCET, pro-oxidant activity, selenocompounds.
Call for Papers in Thematic Issues
Navigating the 2D Universe in Organic Chemistry
This special issue explores the transformative impact of two-dimensional (2D) materials on the realm of organic chemistry, unraveling new possibilities for synthesis, functionalization, and applications of organic compounds. Focused on the unique chemistry within this novel dimension, the issue highlights breakthroughs in the field of 2D organic chemistry. Contributions are ...read more
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