Abstract
Although more than 60% of all cancer patients in Europe and the USA are older than 65 years at the time of diagnosis, elderly patients are generally under-represented in clinical trials. A general consensus on how to treat elderly patients is still far from being achieved.
In this review, we address some of the issues and challenges surrounding the treatment of older cancer patients and radiochemotherapy. We discuss the existing evidence related to radiochemotherapy in the elderly, focusing primarily on the malignancies most commonly seen in older patients and making general treatment recommendations where applicable.
Keywords: Radiochemotherapy, elderly patients, geriatric oncology, clinical trials.
Anti-Cancer Agents in Medicinal Chemistry
Title:Is Effective and Safe a Radiochemotherapy Approach in Elderly Cancer Patients? A Review
Volume: 13 Issue: 9
Author(s): Francesco Fiorica, Antonio Zanghì, Giuliana Pascale, Otilia Nuta, Lino Del Pup, Antonio Stefanelli and Francesco Cartei
Affiliation:
Keywords: Radiochemotherapy, elderly patients, geriatric oncology, clinical trials.
Abstract: Although more than 60% of all cancer patients in Europe and the USA are older than 65 years at the time of diagnosis, elderly patients are generally under-represented in clinical trials. A general consensus on how to treat elderly patients is still far from being achieved.
In this review, we address some of the issues and challenges surrounding the treatment of older cancer patients and radiochemotherapy. We discuss the existing evidence related to radiochemotherapy in the elderly, focusing primarily on the malignancies most commonly seen in older patients and making general treatment recommendations where applicable.
Export Options
About this article
Cite this article as:
Fiorica Francesco, Zanghì Antonio, Pascale Giuliana, Nuta Otilia, Pup Del Lino, Stefanelli Antonio and Cartei Francesco, Is Effective and Safe a Radiochemotherapy Approach in Elderly Cancer Patients? A Review, Anti-Cancer Agents in Medicinal Chemistry 2013; 13 (9) . https://dx.doi.org/10.2174/18715206113136660354
DOI https://dx.doi.org/10.2174/18715206113136660354 |
Print ISSN 1871-5206 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5992 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Bioinspired Microchip Nanoporous Interferometric Sensor for Sensing and Biosensing Applications
Micro and Nanosystems Role of Genetics and Epigenetics in Mucosal, Uveal, and Cutaneous Melanomagenesis
Anti-Cancer Agents in Medicinal Chemistry The Pharmacology of Cyclic Nucleotide-Gated Channels: Emerging from the Darkness
Current Pharmaceutical Design Centrality Measures in Biological Networks
Current Bioinformatics Cigarette Smoke-Induced Proteostasis Imbalance in Obstructive Lung Diseases
Current Molecular Medicine The Extent of Hydroxymethylfurfural Formation in Honey by Heating Temperature and Duration
Letters in Organic Chemistry <i>In-Silico</i> Validation and Fabrication of Matrix Diffusion-Based Polymeric Transdermal Patches for Repurposing Gabapentin Hydrochloride in Neuropathic Pain
CNS & Neurological Disorders - Drug Targets Computational Method for Identifying Malonylation Sites by Using Random Forest Algorithm
Combinatorial Chemistry & High Throughput Screening PSCL: Predicting Protein Subcellular Localization Based on Optimal Functional Domains
Protein & Peptide Letters Mitochondrial Permeability Transition as Target of Anticancer Drugs
Current Pharmaceutical Design Ligands and Therapeutic Perspectives of Adenosine A2A Receptors
Current Pharmaceutical Design Biocombinatorial Selection of Carbohydrate Binding Agents of Therapeutic Significance
Current Drug Discovery Technologies Natural Furano Naphtoquinones from Lapachol: Hydroxyiso-β -Lapachone, Stenocarpoquinone-B and Avicequinone-C
Letters in Organic Chemistry Current Trends in the Chemotherapy of Colorectal Cancer
Current Medicinal Chemistry Optimization and Characterization of Biogenic Silver Nanoparticles Synthesized by Leaves Extract of <i>Alphonsea madraspatana</i>
Current Bioactive Compounds Drug Delivery Systems for Imaging and Therapy of Parkinson's Disease
Current Neuropharmacology Evolution of Reactive mPEG Polymers for the Conjugation of Peptides and Proteins
Current Organic Chemistry Involvement of Cytoskeleton in AhR-Dependent CYP1A1 Expression
Current Drug Metabolism Ultrasound Enhances the Transfection of Plasmid DNA by Non-viral Vectors
Current Pharmaceutical Biotechnology Advances in Quantitative Mass Spectrometry Analysis: Weighing in on Isotope Coding and Label-Free Approaches for Expression and Functional Proteomics
Current Analytical Chemistry