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Current Drug Therapy
ISSN (Print): 1574-8855
ISSN (Online): 2212-3903
VOLUME: 8
ISSUE: 3
DOI: 10.2174/1574885508999131119120237      Price:  $58









Benzimidazole Derivatives as Centerally Acting Agents

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Author(s): Hassan Y. Aboul-Enein and Ahmed A. El Rashedy
Pages 145-154 (10)
Abstract:
Benzimidazole derivatives play an important role in medical field with so many Pharmacological activities, such as selective neuropeptides YY1 receptor antagonists, gamma-amino butyric acid (GABA) agonists, and 5-HT3 antagonists, anticonvulsant and other activities encouraged the development of some more potent and significant compounds. This review presents different substituted benzimidazole derivatives which possess potential along central acting activity.
Keywords:
Anticonvulsant, benzimidazole derivatives, sedative hypnotics, serotoninergic agents.
Affiliation:
Pharmaceutical and Medicinal Chemistry Department, National Research Centre, Dokki, Cairo 12311, Egypt