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Tuberculosis Treatment: The Search For New Drugs
Author(s): Marcus V.N. de Souza
eISBN: 978-1-60805-788-7   ISBN: 978-1-60805-789-4   
Chapter PDF Price: US $ 30
   



Anti-TB Evaluation of Marine Natural Products

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Author(s): Marcus V.N. de Souza
Chapter DOI: 10.2174/9781608057887113010011
Page: 196-216 (21)

Abstract:
The interest of marine natural products in the development of new drugs to treat tuberculosis began in the 1990s with compounds isolated and evaluated in both plant and animal sources becoming an important source of new anti-TB compounds that will be covered in this chapter.
Keywords:
Tuberculosis, Mycobacterium tuberculosis, natural products, sea, semi-synthesis, synthesis, analogues, treatment, multi-drug-resistant tuberculosis (MDR TB), extensive-drug-resistant tuberculosis (XDR TB), target, mechanism of action, biological evaluation, drug development.
Affiliation:
Instituto de Tecnologia em Fármacos - Farmanguinhos, FioCruz - Fundação Oswaldo Cruz, R. Sizenando Nabuco, 100, Manguinhos, 21041-250, Rio de Janeiro, RJ, Brazil.