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Current Analytical Chemistry
ISSN (Print): 1573-4110
ISSN (Online): 1875-6727
VOLUME: 10
ISSUE: 3
DOI: 10.2174/1573411010999131219101823      Price:  $58









Derivatization Coupled to Chemiluminescence Detection

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Author(s): George Z. Tsogas, Dimosthenis L. Giokas and Athanasios G. Vlessidis
Pages 305-319 (15)
Abstract:
In this work, an overview of analytical methods employing derivatization reactions in chemiluminescence detection is presented. Method development, instrumental configurations and hyphenated manifolds, specifically designed or implemented to accommodate CL detection, along with their analytical applications for the determination of a wide variety of organic compounds such as biochemically active substances, pharmaceutical active compounds, environmental pollutants and food constituents, are summarized. The analytical merits of derivatization reactions in chemiluminescence analysis and their potential for the development of sensitive and selective methods are elucidated.
Graphical Abstract:
Keywords:
Chemiluminescence, derivatization, liquid chromatography, capillary electrophoresis.
Affiliation:
Laboratory of Analytical Chemistry, Department of Chemistry, University of Ioannina, 45110, Ioannina, Greece.