Cardioprotective Effect of Resveratrol and Resveratroloside

Title:Cardioprotective Effect of Resveratrol and Resveratroloside

Volume: 11 Issue: 3

Author(s): Sergey E. Naumenko, Tatiana V. Latysheva, Michael A. Gilinsky, Artem D. Rogachev, Nina I. Komarova, Nariman F. Salakhutdinov and Genrikh A. Tolstikov

Affiliation:

Keywords: Cardiovascular disease, in vivo experiments, ischemia-reperfusion, myocardial infarction, myocardial ischemia, natural stilbenes, Pinus sibirica, preconditioning, resveratrol, resveratroloside.

Abstract: Cardioprotective effect of resveratrol and resveratroloside was determined in ischemia-reperfusion experiments on rats. It was found that single intraperitoneal administration of any compound (10 mg/kg) followed by 30-min ischemia and 120-min reperfusion resulted in statistically significant decrease of myocardial infarct area (55.0±4.0% for control group; 40.7±4.4% for the group 1 received resveratrol; 41.6±4.8% for the group 2 received resveratroloside). The cardioprotective effect of resveratroloside was detected for the first time.

Cite this article as:

Naumenko E. Sergey, Latysheva V. Tatiana, Gilinsky A. Michael, Rogachev D. Artem, Komarova I. Nina, Salakhutdinov F. Nariman and Tolstikov A. Genrikh, Cardioprotective Effect of Resveratrol and Resveratroloside, Cardiovascular & Hematological Agents in Medicinal Chemistry 2013; 11 (3) . https://dx.doi.org/10.2174/187152571103140120103302