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Current Organic Chemistry
ISSN (Print): 1385-2728
ISSN (Online): 1875-5348
VOLUME: 18
ISSUE: 6
DOI: 10.2174/1385272819666140201003238      Price:  $58









Recent Developments for the Synthesis of Heterocycles Catalyzed by N-Heterocyclic Carbene

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Author(s): Qiuping Ding, Xiaona Fan and Jie Wu
Pages 700-718 (19)
Abstract:
N-Heterocyclic carbenes (NHCs) as versatile nucleophilic organocatalysts have been extensively studied and also widely applied in organic reactions. The types of organic reactions catalyzed by N-heterocyclic carbenes are broad including benzoin condensation, Stetter reaction, a3-to-d3 umpolung, ring-opening reaction, transesterification, and ring expansion polymerization. This review reports recent developments in the synthesis of heterocycles (such as lactams, lactones, chromones, and benzofuranones) catalyzed by N-heterocyclic carbenes.
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Keywords:
Benzofuranone, chromone, heterocycles, lactam, lactone, N-heterocyclic carbene, organocatalyst.
Affiliation:
School of Pharmacy, Gannan Medical University, Ganzhou, Jiangxi 341000, China and Department of Chemistry, Fudan University, 220 Handan Road, Shanghai 200433, China.