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Current Organic Synthesis
ISSN (Print): 1570-1794
ISSN (Online): 1875-6271
VOLUME: 10
ISSUE: 6
DOI: 10.2174/157017941006140206104352      Price:  $58









A Facile and Quick Synthesis of 9-aryl-substituted-acridines Mediated by DMP

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Author(s): George Bratulescu
Pages 947-950 (4)
Abstract:
An unexpected three components reaction was developed for acridine synthesis in solvent free medium. The reaction is carried out with commercial reagents using of microwaves in a heterogeneous medium in presence of zinc chloride and 2,2-dimethoxypropane (DMP) as water scavenger. Principal advantages of the method are: short time, high yields and easy work-up.
Keywords:
Aromatic acids, acridine, bernthsen reaction, diphenylamine, DMP, water scavenger.
Affiliation:
University of Craiova, Faculty of Chemistry, 13 A.I. Cuza, 200585 Craiova, Romania.