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Current Chromatography
ISSN (Print): 2213-2406
ISSN (Online): 2213-2414
VOLUME: 1
ISSUE: 2
DOI: 10.2174/2213240601666140301001948









Recent Trends in Chiral Separations by Nano Liquid Chromatography and Nano Capillary Electrophoresis

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Author(s): Imran Ali, Zeid A. Al-Othman, Abdulrahman Al-Warthan and Hassan Y. Aboul-Enein
Pages 81-89 (9)
Abstract:
Chiral separation at nano scale is gaining importance in drugs development, proteomic, genomic and environmental sciences. Generally, traces of drugs are found in our body for several weeks. These cannot be detected by conventional analytical techniques. The present article discusses the advances in chiral resolution at nano scale using nano liquid chromatography (NLC) and nano capillary electrophoresis (NCE). The instrumentation, chiral selectors, mechanisms of chiral recognition and future challenges and prospectives have been discussed.
Keywords:
Chiral separations, nano liquid chromatography (NLC), nano capillary electrophoresis (NCE), chiral recognition mechanisms, Challenges and prospectives.
Affiliation:
Department of Chemistry, Jamia Millia Islamia (Central University), New Delhi-110025, India.