Journal Image
The Natural Products Journal
ISSN (Print): 2210-3155
ISSN (Online): 2210-3163
DOI: 10.2174/2210315504666140305231430      Price:  $58

GC-MS Determination of Major Bioactive Constituents and Anti-oxidative Activities of Aqueous Extracts of Cinnamomum burmannii Blume Stem

Author(s): Gabriel A. Akowuah, Mariam Ahmad, Soo C. Tan and Mun F. Yam
Pages 243-248 (6)
The aim of this study was to determine the major boactive constituents, trans-cinnamic acid and transcinnamaldehyde, and anti-oxidative activities of 50% aqueous methanol and water extracts of Cinnamomum burmannii Blume stem bark. Gas chromatography-mass spectrometry (GC-MS) was used to analyse the extracts. The content of trans-cinnalmadeyde quantified in the 50% aqueous methanol and water extracts were 50.14 µg/mg and 12.83 µg/mg of dry extract, respectively. The content of trans-cinnamic acid quantified in the water extract was 49.7 µg/mg of dry extract. Trans-cinnamic acid was not detected in the 50% aqueous methanol (v/v) extract. The extracts demonstrated in vitro antioxidative effects with the 50% aqueous methanol extract being more potent than the water extract.
Cinnamomun burmannii, GC-MS analysis, cinnamaldehyde, cinnamic acid, anti-oxidative activity.
Faculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia.