GC-MS Determination of Major Bioactive Constituents and Anti-oxidative Activities of Aqueous Extracts of Cinnamomum burmannii Blume Stem
Gabriel A. Akowuah, Mariam Ahmad, Soo C. Tan and Mun F. Yam
Pages 243-248 (6)
The aim of this study was to determine the major boactive constituents, trans-cinnamic acid and transcinnamaldehyde,
and anti-oxidative activities of 50% aqueous methanol and water extracts of Cinnamomum burmannii
Blume stem bark. Gas chromatography-mass spectrometry (GC-MS) was used to analyse the extracts. The content of
trans-cinnalmadeyde quantified in the 50% aqueous methanol and water extracts were 50.14 µg/mg and 12.83 µg/mg of
dry extract, respectively. The content of trans-cinnamic acid quantified in the water extract was 49.7 µg/mg of dry extract.
Trans-cinnamic acid was not detected in the 50% aqueous methanol (v/v) extract. The extracts demonstrated in vitro antioxidative
effects with the 50% aqueous methanol extract being more potent than the water extract.
Cinnamomun burmannii, GC-MS analysis, cinnamaldehyde, cinnamic acid, anti-oxidative activity.
Faculty of Pharmaceutical Sciences, UCSI University, 56000, Kuala Lumpur, Malaysia.