Abstract
A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.
Letters in Organic Chemistry
Title:A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives
Volume: 11 Issue: 6
Author(s): Dhiab Jabli, Khaireddine Dridi and Mohamed L. El Efrit
Affiliation:
Keywords: 2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.
Abstract: A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Export Options
About this article
Cite this article as:
Jabli Dhiab, Dridi Khaireddine and El Efrit Mohamed L., A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives, Letters in Organic Chemistry 2014; 11 (6) . https://dx.doi.org/10.2174/1570178611666140311005612
DOI https://dx.doi.org/10.2174/1570178611666140311005612 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
The Dark Side of Stem Cells: Triggering Cancer Progression by Cell Fusion
Current Molecular Medicine Drug-Lipid Membrane Interaction Mechanisms Revealed Through Molecular Simulations
Current Physical Chemistry Synthesis, Topoisomerase I Inhibitory and Cytotoxic Activities of Chromone Derivatives
Medicinal Chemistry Mitochondrial Abnormalities in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease
Current Alzheimer Research Pros and Cons of Medical Cannabis use by People with Chronic Brain Disorders
Current Neuropharmacology Modulation of Cytokine Network in the Comorbidity of Schizophrenia and Tuberculosis
Current Topics in Medicinal Chemistry Detection of Diuretic Doping by Capillary Electrophoresis and Electrochemical Technology: A Mini-Review
Current Pharmaceutical Analysis An Update of the Classical and Novel Methods Used for Measuring Fast Neurotransmitters During Normal and Brain Altered Function
Current Neuropharmacology 2D and 3D-QSAR analysis of pyrazole-thiazolinone derivatives as EGFR kinase inhibitors by CoMFA and CoMSIA
Current Computer-Aided Drug Design Natural Compounds and Plant Extracts as Therapeutics Against Chronic Inflammation in Alzheimer's Disease - A Translational Perspective
CNS & Neurological Disorders - Drug Targets Spectral Methods of Characterizing the Conformational Changes of Glycated Goat Liver Cystatin
Current Proteomics Bioavailability and Pharmacokinetics of Genistein: Mechanistic Studies on its ADME
Anti-Cancer Agents in Medicinal Chemistry A Water-Soluble Fenbendazole (FBZ) Formulation for Treating Pinworm Infections in Laboratory Animals
Drug Delivery Letters Nutraceuticals: Beyond the Diet Before the Drugs
Current Bioactive Compounds Synthesis of 4-(5-chloro-3-methyl-1-phenyl-1H-pyrazol-4-yl)-6-(substituted phenyl)pyrimidin-2-ol Analogues as Anti-Inflammatory and Analgesic Agents
Letters in Drug Design & Discovery Biginelli Reaction of Vicinal Diols: A New Route for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-One Derivatives
Letters in Organic Chemistry Matrix Metalloproteinases as Drug Targets in Preeclampsia
Current Drug Targets Mechanisms of Melatonin in Alleviating Alzheimer’s Disease
Current Neuropharmacology Laccases in Pharmaceutical Chemistry: A Comprehensive Appraisal
Mini-Reviews in Organic Chemistry Circulating Meteorin-like Levels in Patients with Type 2 Diabetes Mellitus: A Meta-Analysis
Current Pharmaceutical Design