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Letters in Organic Chemistry
ISSN (Print): 1570-1786
ISSN (Online): 1875-6255
VOLUME: 11
ISSUE: 6
DOI: 10.2174/1570178611666140311005612      Price:  $58









A Convenient Synthesis of New 2-Cyanomethylthieno[3,2-e][1,2,4]- triazolo[1,5-c]pyrimidine Derivatives

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Author(s): Dhiab Jabli, Khaireddine Dridi and Mohamed L. El Efrit
Pages 403-408 (6)
Abstract:
A new series of 2-cyanomethylthienotriazolopyrimidines has been synthesized in good yield through a facile method using substituted aminothiophene-3-carbonitrile as building block and cyanoacetic acid hydrazide as reagent in one framework. The structure of the synthesized compounds was established on the basis of their mass and spectral data.
Graphical Abstract:
Keywords:
2-Aminothiophene-3-carbonitrile, iminoethers, iminithieopyrimidin-3-ylamine, cyanoacetic acid hydrazide, thienotriazolopyrimidine.
Affiliation:
Laboratory of Organic Chemistry, Department of Chemistry, Faculty of Sciences, El Manar University, El Manar II, Tunis 1060, Tunisia and Department of Chemistry, College of Sciences and Arts, Qassim University, Al-Rass, 53, Kingdom of Saudi Arabia.