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Mini-Reviews in Medicinal Chemistry
ISSN (Print): 1389-5575
ISSN (Online): 1875-5607
VOLUME: 14
ISSUE: 4
DOI: 10.2174/1389557514666140329200745      Price:  $58









[1, 2, 4]-Oxadiazoles: Synthesis and Biological Applications

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Author(s): Rajesh O. Bora, Bashir Dar, Vidya Pradhan and Mazahar Farooqui
Pages 355-369 (15)
Abstract:
In the present article synthesis and medicinal applications of [1, 2, 4] oxadiazoles are reviewed. The oxadiazoles have a wide range of applications such as Antitussive, Anti-inflammatory, Anaesthetic, Vasodilator, anthelmintic, antiallergic, antiplatelet effects in vitro, antithrombotic properties in vivo, etc. Many researchers have synthesized novel heterocyclic compounds containing oxadiazoles with the concept of bioisosterism.
Keywords:
Anaesthetic angent, anti-inflammatory, anti-tumor agents, heterocycles, one pot synthesis, [1, 2, 4] oxadiazoles, synthetic methods.
Affiliation:
Post Graduate and Research centre, Maulana Azad College, Aurangabad, and Indian Institute of Integrative Medicine Jammu 180001.