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Current Bioactive Compounds
ISSN (Print): 1573-4072
ISSN (Online): 1875-6646
VOLUME: 9
ISSUE: 4
DOI: 10.2174/157340720904140404151439









Comparison of Artemisia annua Bioactivities between Traditional Medicine and Chemical Extracts

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Author(s): Ahmed Nageeb, Azza Al-Tawashi, Abdul-Hamid Mohammad Emwas, Zeyad Abdel-Halim Al-Talla and Nahla Al-Rifai
Pages 324-332 (9)
Abstract:
The present work investigates the efficacy of using Artemisia annua in traditional medicine in comparison with chemical extracts of its bioactive molecules. In addition, the effects of location (Egypt and Jericho) on the bioactivities of the plant were investigated. The results showed that water extracts of Artemisia annua from Jericho have stronger antibacterial activities than organic solvent extracts. In contrast, water and organic solvent extracts of the Artemisia annua from Egypt do not have anti-bacterial activity. Furthermore, while the methanol extract of EA displayed high anticancer affects, the water extract of Egypt and the extracts of Jericho did not show significant anticancer activity. Finally, the results showed that the methanol and water extracts of Jericho had the highest antioxidant activity, while the extracts of Egypt had none. The current results validate the scientific bases for the use of Artemisia annua in traditional medicine. In addition, our results suggest that the collection location of the Artemisia annua has an effect on its chemical composition and bioactivities.
Keywords:
Artemisia, bioactivities, NMR, antibacterial, anticancer.
Affiliation:
Research and Development, Qatar Foundation, PO Box: 5825, Doha Qatar.