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Current Gene Therapy
ISSN (Print): 1566-5232
ISSN (Online): 1875-5631
Epub Abstract Ahead of Print
DOI: 10.2174/1566523214666140424145305      Price:  $95

Progress of in Vivo Electroporation in the Rodent Brain

Author(s): Xue Feng Ding, De Lin Ma, Qiang Zhang, Wei Peng, Ming Fan and William Z. Suo
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In vivo electroporation is one of the most efficient methods for introducing the nucleic acids into the target tissues, and thus plays a pivotal role in gene therapeutic studies. In vivo electroporation in rodent brains often involves in injection of nucleic acids into the brain ventricle or specific area and then applying appropriate electrical field to the correct area. Better understanding the progress of electroporation in rodent brain may further facilitate gene therapeutic studies on some brain disorders. For this purpose, we briefly summarized the advantages, the procedures and recent progress of transferring nucleic acids into the rodent brain using in vivo electroporation
Department of Cognitive sciences, Beijing Institute of Basic Medical Sciences, Tai ping Road 27, Beijing 100850, P. R. China