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Letters in Organic Chemistry
ISSN (Print): 1570-1786
ISSN (Online): 1875-6255
VOLUME: 11
ISSUE: 8
DOI: 10.2174/157017861108140613162852      Price:  $58









Synthesis of New and Known Dicoumarols in Aqueous Media: A Green and Convenient Procedure Promoted by Titanium(IV) Oxide Nanoparticles

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Author(s): Saeed Khodabakhshi, Mozhgan Shahamirian and Mojtaba Baghernejad
Pages 596-600 (5)
Abstract:
A simple and green method is reported for the completely chemoselective synthesis of some new dicoumarol derivatives {3,3'-(2-aryl-2-oxoethylidene)bis[4-hydroxycoumarin]s} from the reaction of 4-hydroxycoumarin with arylglyoxals in a molar ratio of 2:1 respectively. The reactions efficiently promoted by titanium(IV) oxide nanoparticles as a heterogeneous catalyst via an on water process. Catalyst loading is very low and it shows recyclability.
Graphical Abstract:
Keywords:
Titanium(IV) oxide nanoparticles, chemoselectivity, 3, 3'-(2-aryl-2-oxoethylidene)bis[4-hydroxycoumarin]s, catalysts, arylglyoxal.
Affiliation:
Young Researchers and Elite Club, Gachsaran Branch, Islamic Azad University, Gachsaran, Iran.