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Mini-Reviews in Medicinal Chemistry
ISSN (Print): 1389-5575
ISSN (Online): 1875-5607
VOLUME: 14
ISSUE: 7
DOI: 10.2174/1389557514666140622204608      Price:  $58









Benzocoumarins: Isolation, Synthesis, and Biological Activities

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Author(s): Hai-Ning Lv, Peng-Fei Tu and Yong Jiang
Pages 603-622 (20)
Abstract:
Benzocoumarins are coumarins with a phenyl group bonded to 3,4-, 5,6-, 6,7-, or 7,8-positions. Over the past years, significant efforts have been made not only to isolate the novel structural analogs of benzocoumarins with prominent bioactivities but also to design new synthetic methods to synthesize benzocoumarins with better or novel biological properties. The aim of this review is to provide the readers with an overview of the research progress of benzocoumarins from 1953 to May 2014, covering its isolation, synthesis, and biological activities.
Keywords:
Benzocoumarins, biological activities, isolation, natural products, synthesis.
Affiliation:
State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China.