Abstract
Achilles tendon injuries are common but complex in nature. Healing occurs via scar tissue formation leading to poor patient outcomes. Currently surgical and non-surgical treatment leads to suboptimal tendon healing and has complications. Tissue engineering is an advancing field that can either augment surgical repair or provide an alternative method for Achilles tendon repair. This article will explore the principles behind tissue engineering in Achilles tendon repair. Furthermore it will describe the current literature regarding the different types of stem cells used in Achilles tendon repair, how different growth factors augment tendon repair, as well as the role of biomaterials in tissue engineering.
Keywords: Achilles tendon, growth factors, stem cells, tissue engineering.
Current Stem Cell Research & Therapy
Title:The Role of Tissue Engineering in Achilles Tendon Repair: A Review
Volume: 10 Issue: 1
Author(s): Varun Sahni, Saket Tibrewal, Lianne Bissell and Wasim S. Khan
Affiliation:
Keywords: Achilles tendon, growth factors, stem cells, tissue engineering.
Abstract: Achilles tendon injuries are common but complex in nature. Healing occurs via scar tissue formation leading to poor patient outcomes. Currently surgical and non-surgical treatment leads to suboptimal tendon healing and has complications. Tissue engineering is an advancing field that can either augment surgical repair or provide an alternative method for Achilles tendon repair. This article will explore the principles behind tissue engineering in Achilles tendon repair. Furthermore it will describe the current literature regarding the different types of stem cells used in Achilles tendon repair, how different growth factors augment tendon repair, as well as the role of biomaterials in tissue engineering.
Export Options
About this article
Cite this article as:
Sahni Varun, Tibrewal Saket, Bissell Lianne and Khan S. Wasim, The Role of Tissue Engineering in Achilles Tendon Repair: A Review, Current Stem Cell Research & Therapy 2015; 10 (1) . https://dx.doi.org/10.2174/1574888X09666140710103154
DOI https://dx.doi.org/10.2174/1574888X09666140710103154 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Relationship Between Oxidative Stress, Tau Level and Antioxidant Mechanisms of the KEAP-1/NRF-2/HO-1 in Children with Hydrocephalus
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry Defective Autophagy in Fibroblasts May Contribute to Fibrogenesis in Autoimmune Processes
Current Pharmaceutical Design Metformin Restrains Pancreatic Duodenal Homeobox-1 (PDX-1) Function by Inhibiting ERK Signaling in Pancreatic Ductal Adenocarcinoma.
Current Molecular Medicine MicroRNAs as Early Biomarkers in Obesity and Related Metabolic and Cardiovascular Diseases
Current Pharmaceutical Design Prevention and Treatment of Diabetic Retinopathy: Evidence from Large, Randomized Trials. The Emerging Role of Fenofibrate
Reviews on Recent Clinical Trials Complement Components, C3 and C4, and the Metabolic Syndrome
Current Diabetes Reviews Global Life-Long Health Benefits of Repression of Hypothalamic NPY System by Central Leptin Gene Therapy
Current Topics in Medicinal Chemistry Integrated, Molecular Engineering Approaches to Develop Prostate Cancer Gene Therapy
Current Gene Therapy Epilepsy, Regulation of Brain Energy Metabolism and Neurotransmission
Current Medicinal Chemistry Oxidative Stress, Sarcopenia, Antioxidant Strategies and Exercise: Molecular Aspects
Current Pharmaceutical Design Allele Frequencies of Two Main Metformin Transporter Genes: SLC22A1 rs628031 A>G and SLC47A1 rs2289669 G>A among the Javanese Population in Indonesia
Current Pharmacogenomics and Personalized Medicine Spirocyclic Nucleosides in Medicinal Chemistry: An Overview
Mini-Reviews in Medicinal Chemistry Chitosan-Coated Alginate Nanoparticles Enhanced Absorption Profile of Insulin Via Oral Administration
Current Drug Delivery Antineoplastic Activities, Apoptotic Mechanism of Action and Structural Properties of a Novel Silver(I) Chelate
Current Medicinal Chemistry The Future of Diabetes Management by Healthy Probiotic Microorganisms
Current Diabetes Reviews Molecular Determinants of the Cardiometabolic Phenotype
Endocrine, Metabolic & Immune Disorders - Drug Targets Synthesis, Biological Evaluation, and QPLD Studies of Piperazine Derivatives as Potential DPP-IV Inhibitors
Medicinal Chemistry Dampening the Progression of Dementia
Current Neurovascular Research Cellular and Physiological Effects of Arginine
Mini-Reviews in Medicinal Chemistry Should Subfertile Women be Screened for Eating Disorders?
Current Psychiatry Reviews