INTRODUCTION TO EDITION
The objective of this edition is to present hypothesis and the main evidence about areas of nutrition, immunology, cancer,
diabetes and infectious diseases. The articles presented in this edition untitled “Nutrition and immunology in Diabetes, cancer
and infectious diseases”, are result of three mini reviews that summarize the main studies that have addressed these issues and
described with detail the mechanism of different nutrient over some pathologies.
The first mini review, “The Role of the Healthy Dietary Intake in Women with Human Papilloma Virus”, is about the most
common viral sexually transmitted infection in humans and the lesions caused by HPV are under the influence of immunological
factors. Nutritional status and intake adequate amounts of macronutrients (protein, carbohydrates and fat) and micronutrients
(mainly zinc, folic acid and vitamin A), facilitate appropriate functioning of the immune system [1, 2]. Several studies
have reported beneficial associations with the intake of some micronutrients, among them being mainly vitamin A and C and
folic acid. These compounds have a chemopreventive effect due to their antioxidant action . This evidence reflect the importance
of consider a dietary and nutritional approach in treating these infection disease.
The second mini review “The Role of NO-cGMP Signaling Pathway in Pancreatic Beta-cell Function” highlights that in the
last decades, there has been an increasing evidence on the role of nitric oxide (NO) on the function of pancreatic islet cells, but
it has not been fully elucidated. There are many reports about the negative effects of NO on the beta-cell function and its survival
[3, 4]. The study of the main mechanisms, and the role of NO in beta-cells, may lead to new aspects in insulin secretion
modulation and therefore, to the establishment of novel therapeutic targets for diabetes treatment .
The third article, “Anti-inflammatory and Antitumor Properties of Eriobotrya Japonica Lindl: Mini-Review”, is about the
anti-inflammatory and anti-tumor properties of Eriobotrya japónica extracts and isolated phytochemical compounds, where the
Astringent leaves of loquat have been used to treat asthma, chronic bronchitis, coughs, phlegm, high fever, cancer, diabetes,
and gastroenteric disorders  and are widely used as a herbal remedy in many countries. But it is important to continue to
search their effects.
The nutrition aspects are important for understanding the knowledge about inflammation, metabolic disorder, and damage in
organs and systems . This edition covers the main diseases that may have some form of prevention or healing coming from
the nutrition area.
Medicine and Nutrition Department, Campus Leon, University of Guanajuato Observatorio Universitario en Seguridad Alimentaria y Nutricional de Guanajuato.