Abstract
A novel 2-(methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin-5(4H)-one was synthesized employing dimethyl N-cyanoimidodithiocarbonate and 3-hydrazinyl-2-naphthoic acid as building blocks. Chemical transformation of the inherent lactam group in the target molecule provided access to a variety of heterocylic derivatives. The obtained compounds are characterized and confirmed by NMR, IR, and HREI-MS analyses.
Keywords: 3-hydrazinyl-2-naphthoic acid, cyclocondensation, dimethyl N-cyanoimidodithiocarbonate.
Letters in Organic Chemistry
Title:Synthesis of Novel 2-(Methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin- 5-(4H)-one and its Derivatives
Volume: 11 Issue: 10
Author(s): Rashad A. Al-Salahi, Mohamed S. Marzouk, Hazem A. Ghabbour and Fun H. Kun
Affiliation:
Keywords: 3-hydrazinyl-2-naphthoic acid, cyclocondensation, dimethyl N-cyanoimidodithiocarbonate.
Abstract: A novel 2-(methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin-5(4H)-one was synthesized employing dimethyl N-cyanoimidodithiocarbonate and 3-hydrazinyl-2-naphthoic acid as building blocks. Chemical transformation of the inherent lactam group in the target molecule provided access to a variety of heterocylic derivatives. The obtained compounds are characterized and confirmed by NMR, IR, and HREI-MS analyses.
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Cite this article as:
Al-Salahi A. Rashad, Marzouk S. Mohamed, Ghabbour A. Hazem and Kun H. Fun, Synthesis of Novel 2-(Methylthio)benzo[g][1,2,4]triazolo[1,5-a]quinazolin- 5-(4H)-one and its Derivatives, Letters in Organic Chemistry 2014; 11 (10) . https://dx.doi.org/10.2174/1570178611666140813205111
DOI https://dx.doi.org/10.2174/1570178611666140813205111 |
Print ISSN 1570-1786 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6255 |
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