Abstract
A highly efficient method for synthesis of multifunctionalized benzenes by one-pot multicomponent condensation between malononitrile, substituted aldehyde and cycloheptanone catalyzed by Zn-VCO3 hydrotalcite is reported. With water as solvent, this green chemistry reaction entails mild conditions. It is atom-efficient, high-yielding and pertinent to an extensive variety of multicomponent reactions.
Keywords: Green chemistry, multicomponent reaction, multifunctionalized benzenes, reusable catalyst, water as a solvent, Zn-VCO3 hydrotalcite.
Graphical Abstract
Call for Papers in Thematic Issues
Exploring the Role of Chemical Graph Theory in Advancing Current Organic Synthesis
Organic synthesis is a fundamental discipline in chemistry, crucial for the creation of complex molecules with diverse applications in pharmaceuticals, materials science, and beyond. However, the process of designing efficient synthetic routes for target molecules remains challenging. Chemical graph theory, a branch of theoretical chemistry, offers powerful tools for understanding ...read more
Photoswitches for Molecular Recognition
This Special Issue would cover the hot topics on synthesis and chemical and photophysical characterization of new photoswitchable derivatives and their applications on molecular recognition of metabolites and biological active compounds, both in physiological medium and in living cells. Photoswitches are compounds that can change their conformation or properties in ...read more
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