Abstract
Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Current Stem Cell Research & Therapy
Title:Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review
Volume: 10 Issue: 5
Author(s): Zhenhua Yang, Yanjiao Li, Xiaojie Ma, Lin Shen, Zhihe Zhao and Fang Jin
Affiliation:
Keywords: Hertwig's epithelial root sheath, epithelial cell rests Malassez, periodontium development, periodontal regeneration, cementogenesis, stem cells.
Abstract: Predictable and complete periodontal regeneration following periodontitis has been the ultimate goal of periodontal treatment. It has been recognized that Hertwig’s epithelial root sheath (HERS) cells play a crucial role in cementogenesis and root formation. As the descendants of HERS and unique odontogenic epithelium in the adult periodontium, epithelial cell rests of Malassez (ERM) have long been considered as quiescent epithelial remnants devoid of structure and function. Here we will present an overview of our present understanding and putative functions of the ERM in the regeneration of periodontal tissues.
Export Options
About this article
Cite this article as:
Yang Zhenhua, Li Yanjiao, Ma Xiaojie, Shen Lin, Zhao Zhihe and Jin Fang, Role of the Epithelial Cell Rests of Malassez in Periodontal Homeostasis and Regeneration - A Review, Current Stem Cell Research & Therapy 2015; 10 (5) . https://dx.doi.org/10.2174/1574888X10666150312100957
DOI https://dx.doi.org/10.2174/1574888X10666150312100957 |
Print ISSN 1574-888X |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3946 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Subject Index to Volume 1
Current Drug Delivery Detection of Antibodies Against Synthetic Peptides Mimicking Ureases Fragments in Sera of Rheumatoid Arthritis Patients
Protein & Peptide Letters Matrixmetalloproteinase Inhibitors: Promising Therapeutic Targets Against Cancer
Current Pharmaceutical Design Is uPAR the Centre of a Sensing System Involved in the Regulation of Inflammation?
Current Medicinal Chemistry - Anti-Inflammatory & Anti-Allergy Agents Recent Advances in Bacteriocin Application as Antimicrobials
Recent Patents on Anti-Infective Drug Discovery Histone Modification in Osteogenic Differentiation of Skeletal Stem Cells
Current Stem Cell Research & Therapy Anti-Platelet Treatment of Middle-Sized Abdominal Aortic Aneurysms
Current Vascular Pharmacology Potential Therapeutic Benefits of Dipyridamole in COVID-19 Patients
Current Pharmaceutical Design Integrins Modulate Cellular Fibrogenesis at Multiple Levels: Regulation of TGF-β Signaling
Endocrine, Metabolic & Immune Disorders - Drug Targets Quality by Design and Evaluation of Crosslinked Chitosan Microspheres for the Controlled Delivery of Doxycycline Hyclate
Drug Delivery Letters Antimicrobial Development in the Era of Emerging Resistance
Mini-Reviews in Medicinal Chemistry Intestinal MicrobiOMICS to Define Health and Disease in Human and Mice
Current Pharmaceutical Biotechnology Editorial (Thematic Issue: Molecular, Cellular and Pharmaceutical Aspects of Biomaterials in Dentistry and Oral and Maxillofacial Surgery. International Cooperation, Translational Research and Transdisciplinarity)
Current Pharmaceutical Biotechnology Suppression of Virulence of Porphyromonas gingivalis by Potent Inhibitors Specific for Gingipains
Current Protein & Peptide Science Molecular Mechanisms Regulating Matrix Metalloproteinases
Current Topics in Medicinal Chemistry Neurodegenerative Diseases and Flavonoids: Special Reference to Kaempferol
CNS & Neurological Disorders - Drug Targets Functions of S100 Proteins
Current Molecular Medicine Application of Molecular Topology to the Search of Novel NSAIDs: Experimental Validation of Activity
Letters in Drug Design & Discovery MiR-147: Functions and Implications in Inflammation and Diseases
MicroRNA A Review of Five Automatic Point Correspondence Methods for Application on Medical Images
Current Medical Imaging