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Current Organic Chemistry

Editor-in-Chief

ISSN (Print): 1385-2728
ISSN (Online): 1875-5348

Recent Developments in the Fluorofunctionalization of Alkenes

Author(s): Xiu-Hua Xu and Feng-Ling Qing

Volume 19, Issue 16, 2015

Page: [1566 - 1578] Pages: 13

DOI: 10.2174/1385272819666150429230707

Price: $65

Abstract

The difunctionalization of unsaturated carbon-carbon double bond is a powerful strategy for the construction of compounds with various functional groups. The present review aims to highlight the recent developments in the fluorination of alkenes with concomitant introduction of additional functional groups. Various methods are described for both intramolecular and intermolecular fluorofunctionalization of alkenes. These fluorofunctionalization processes should find broad applications in pharmaceutical and material industries.

Keywords: Alkene, difunctionalization, fluorine, intermolecular, intramolecular, regioselective.

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