Abstract
An efficient and one-pot method for the preparation of 3,4-dihydropyrimidin-2(1H)- ones/thiones is described. Benzyltriphenylphosphonium chloride (BTPPC) under solvent free conditions catalyzes this multi-component condensation reaction to afford the corresponding dihydropyrimidinones/thiones in good yields.
Keywords: Multi-component condensation, one-pot synthesis, benzyltriphenylphosphonium chloride, 3, 4-dihydropyrimidin-2(1H)-ones/thiones, solvent-free.
Graphical Abstract
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