Abstract
The biological activities of the calix[n]arenes have been extensively reported on, with regard to various forms of life ranging from self-replicating systems, such as, viruses, through bacteria, fungi and mammalian cells to human beings. This article reviews more than one hundred different calix[n]arenes classified according to their biological effects directly observed on living species. These macrocyclic molecules have been reported as detoxifying agents, as having antibacterial, antiviral, anticoagulant, anticancer, antifungal activities, as membrane protein modulators / extracters, drug transporters and fluorescent probes. Special in vivo sections, have been inserted when possible for each biological effect showing the impact of the calix[n]arenes on whole living system such as animals or humans.
Keywords: Calix[n]arenes, in vitro, in vivo, cells, biological applications, Active Pharmaceutical Ingredients.
Current Organic Chemistry
Title:Cellular and in Vivo Biological Activities of the Calix[n]arenes
Volume: 19 Issue: 23
Author(s): Yannick Tauran, Anthony W. Coleman, Florent Perret and Beomjoon Kim
Affiliation:
Keywords: Calix[n]arenes, in vitro, in vivo, cells, biological applications, Active Pharmaceutical Ingredients.
Abstract: The biological activities of the calix[n]arenes have been extensively reported on, with regard to various forms of life ranging from self-replicating systems, such as, viruses, through bacteria, fungi and mammalian cells to human beings. This article reviews more than one hundred different calix[n]arenes classified according to their biological effects directly observed on living species. These macrocyclic molecules have been reported as detoxifying agents, as having antibacterial, antiviral, anticoagulant, anticancer, antifungal activities, as membrane protein modulators / extracters, drug transporters and fluorescent probes. Special in vivo sections, have been inserted when possible for each biological effect showing the impact of the calix[n]arenes on whole living system such as animals or humans.
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Cite this article as:
Tauran Yannick, Coleman W. Anthony, Perret Florent and Kim Beomjoon, Cellular and in Vivo Biological Activities of the Calix[n]arenes, Current Organic Chemistry 2015; 19 (23) . https://dx.doi.org/10.2174/1385272819666150608222114
DOI https://dx.doi.org/10.2174/1385272819666150608222114 |
Print ISSN 1385-2728 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5348 |
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