Abstract
The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde, 4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[ 3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.
Keywords: Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles, microwave assisted synthesis, pyrazoles.
Current Microwave Chemistry
Title:Microwave Assisted Reactions of 5-Amino-1, 3-disubstituted Pyrazoles with Some Benzaldehydes
Volume: 3 Issue: 2
Author(s): Agnieszka Puchala, Magdalena Marcinkowska and Danuta Rasala
Affiliation:
Keywords: Aldehydes, bis-pyrazolo[3, 4-b;4’, 3’-e]pyridines, diamine derivatives, N-heterocycles, microwave assisted synthesis, pyrazoles.
Abstract: The microwave-promoted reactions of 5-amino-1,3-disubstituted pyrazoles with benzaldehyde, 4-chloro- and 4-nitrobenzaldehydes are presented. The use of microwave irradiation with variable input power leads to different products, such as Schiff bases, diamine derivatives and bispyrazolo[ 3,4-b;4’3’-e]pyridines in moderate to excellent yields and high purities.
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Cite this article as:
Puchala Agnieszka, Marcinkowska Magdalena and Rasala Danuta, Microwave Assisted Reactions of 5-Amino-1, 3-disubstituted Pyrazoles with Some Benzaldehydes, Current Microwave Chemistry 2016; 3 (2) . https://dx.doi.org/10.2174/2213335602666150706182707
DOI https://dx.doi.org/10.2174/2213335602666150706182707 |
Print ISSN 2213-3356 |
Publisher Name Bentham Science Publisher |
Online ISSN 2213-3364 |
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