Abstract
Black cumin, Nigella sativa (NS), which is also known as black seed (Kalijeera), is an annual flowering plant from the Ranunculaceae family. Its seeds were used in most ancient medical systems. For ages it was considered to be a panacea. It is rooted in our traditions and has flourished into an intensively investigated medicinal plant. There is an abundance of reports on the biological activities of Nigella sativa seeds or extracts. The spectrum of its activity is impressive and includes antimicrobial, antiviral, anticancer, antimalarial as well as an antidiabetic or immunostimulatory potency. In this review both in vitro and in vivo results are gathered and the results of clinical trials are discussed. Patents and the industrial use of NS as both a food supplement and as animal feed are also mentioned. An analysis of the literature data showed that the comprehensive investigations of Nigella sativa are fairly well translated into actual everyday healthcare. The data presented in this review reveals future use of this valuable plant.
Keywords: Anticancer, antimicrobial, gastroprotective, Nigella sativa, thymoquinone.
The Natural Products Journal
Title:Nigella sativa – A Functional Spice From A Pharaoh’s Tomb to Modern Healthcare
Volume: 6 Issue: 1
Author(s): Anna Mrozek-Wilczkiewicz and Robert Musiol
Affiliation:
Keywords: Anticancer, antimicrobial, gastroprotective, Nigella sativa, thymoquinone.
Abstract: Black cumin, Nigella sativa (NS), which is also known as black seed (Kalijeera), is an annual flowering plant from the Ranunculaceae family. Its seeds were used in most ancient medical systems. For ages it was considered to be a panacea. It is rooted in our traditions and has flourished into an intensively investigated medicinal plant. There is an abundance of reports on the biological activities of Nigella sativa seeds or extracts. The spectrum of its activity is impressive and includes antimicrobial, antiviral, anticancer, antimalarial as well as an antidiabetic or immunostimulatory potency. In this review both in vitro and in vivo results are gathered and the results of clinical trials are discussed. Patents and the industrial use of NS as both a food supplement and as animal feed are also mentioned. An analysis of the literature data showed that the comprehensive investigations of Nigella sativa are fairly well translated into actual everyday healthcare. The data presented in this review reveals future use of this valuable plant.
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Cite this article as:
Mrozek-Wilczkiewicz Anna and Musiol Robert, Nigella sativa – A Functional Spice From A Pharaoh’s Tomb to Modern Healthcare, The Natural Products Journal 2016; 6 (1) . https://dx.doi.org/10.2174/2210315506999151209100649
DOI https://dx.doi.org/10.2174/2210315506999151209100649 |
Print ISSN 2210-3155 |
Publisher Name Bentham Science Publisher |
Online ISSN 2210-3163 |
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Recent Advances in Biotransformation of Bioactive Terpenoids using Aspergillus niger
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