Abstract
Onychomycosis (fungal nail infections) is very common worldwide but is fortunately not often lethal. Several powerful drugs have been introduced into clinical practice in recent years, but these infections remain difficult to cure primarily due to the difficulty of penetration of drug to the site of the infection in therapeutic concentrations. The nature of the disease, the causative fungi, and the characteristics of the drugs employed to treat this condition are discussed in this review.
Keywords: Antifungal drugs, onychomycosis, dermatophytes, griseofulvin, azoles, polyene macrolides, allyl amines, ciclopirox, tavaborole, tea tree oil.
Current Medicinal Chemistry
Title:Onychomycosis and its Chemotherapy
Volume: 23 Issue: 16
Author(s): Anwer Basha, Fatima Basha, Syed K. Ali, Paul R. Hanson, Berl R. Oakley, Heather Hajovsky and Lester A. Mitscher
Affiliation:
Keywords: Antifungal drugs, onychomycosis, dermatophytes, griseofulvin, azoles, polyene macrolides, allyl amines, ciclopirox, tavaborole, tea tree oil.
Abstract: Onychomycosis (fungal nail infections) is very common worldwide but is fortunately not often lethal. Several powerful drugs have been introduced into clinical practice in recent years, but these infections remain difficult to cure primarily due to the difficulty of penetration of drug to the site of the infection in therapeutic concentrations. The nature of the disease, the causative fungi, and the characteristics of the drugs employed to treat this condition are discussed in this review.
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Cite this article as:
Basha Anwer, Basha Fatima, Ali K. Syed, Hanson R. Paul, Oakley R. Berl, Hajovsky Heather and Mitscher A. Lester, Onychomycosis and its Chemotherapy, Current Medicinal Chemistry 2016; 23 (16) . https://dx.doi.org/10.2174/0929867323666160411130103
DOI https://dx.doi.org/10.2174/0929867323666160411130103 |
Print ISSN 0929-8673 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-533X |
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