Abstract
Type 2 diabetes is a disorder of ages, which has become deadlier because of life style modification and adaptation in the modern world. Extensive sudy of the pathophysiology of diabetes has opened up various mysteries about the disease and has helped us to know and understand diabetes in a better manner. Presently, we know many minute details about the pathophysiology of diabetes mellitus and are thus well weaponed to fight against it. Treatment regime has been evolving daily. Besides the conventional anti-diabetic drugs, integrated medicinal approach for treating diabetes type 2 with a compact therapeutic approach consisting of various targeted treatments for individual symptoms associated with the disease are being tried currently. Diabetes associated complications like high blood pressure, hyperglycemia, microalbumuria, dyslipidemia, pro -coagulation, etc. are being targeted and dealt with individually in the integrative medicinal approach. The results are promising and thus ignite hope for a better and more successful handling of diabetes and diabetes related pathophysiological complications in near future.
Keywords: Anti-diabetic drugs, drug development, hyperglycaemia, diabetes type 2.
Current Drug Discovery Technologies
Title:Drug Discovery and Development of Type 2 Diabetes Mellitus: Modern-Integrative Medicinal Approach
Volume: 13 Issue: 2
Author(s): Debosree Ghosh and Pratap Parida
Affiliation:
Keywords: Anti-diabetic drugs, drug development, hyperglycaemia, diabetes type 2.
Abstract: Type 2 diabetes is a disorder of ages, which has become deadlier because of life style modification and adaptation in the modern world. Extensive sudy of the pathophysiology of diabetes has opened up various mysteries about the disease and has helped us to know and understand diabetes in a better manner. Presently, we know many minute details about the pathophysiology of diabetes mellitus and are thus well weaponed to fight against it. Treatment regime has been evolving daily. Besides the conventional anti-diabetic drugs, integrated medicinal approach for treating diabetes type 2 with a compact therapeutic approach consisting of various targeted treatments for individual symptoms associated with the disease are being tried currently. Diabetes associated complications like high blood pressure, hyperglycemia, microalbumuria, dyslipidemia, pro -coagulation, etc. are being targeted and dealt with individually in the integrative medicinal approach. The results are promising and thus ignite hope for a better and more successful handling of diabetes and diabetes related pathophysiological complications in near future.
Export Options
About this article
Cite this article as:
Ghosh Debosree and Parida Pratap, Drug Discovery and Development of Type 2 Diabetes Mellitus: Modern-Integrative Medicinal Approach, Current Drug Discovery Technologies 2016; 13 (2) . https://dx.doi.org/10.2174/1570163813666160414105327
DOI https://dx.doi.org/10.2174/1570163813666160414105327 |
Print ISSN 1570-1638 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6220 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
- Announcements
Related Articles
-
Roles and Regulation of the Transcription Factor CREB in Pancreatic β -Cells
Current Molecular Pharmacology Endocrinological Aspects of Proteinuria and Podocytopathy in Diabetes: Role of the Aldosterone/Mineralocorticoid Receptor System
Current Diabetes Reviews L-/N-type Calcium Channel Blockers and Proteinuria
Current Hypertension Reviews α-Glucosidase Inhibitory Effect and Antioxidant Activity of the Extracts of Eighteen Plant Traditionally Used in Algeria for Diabetes
Current Enzyme Inhibition Involvement of Cysteine Proteases in Cancer
Current Medicinal Chemistry Prevalence and Related Factors of Sarcopenia in Community-dwelling Elderly with Long-term Care Insurance
Reviews on Recent Clinical Trials The Prevalence of the Classical and Non-Classical Cardiovascular Risk Factors in Multiple Sclerosis Patients
CNS & Neurological Disorders - Drug Targets Endophthalmitis
Anti-Infective Agents in Medicinal Chemistry Diabetes and Gestational Hypertension
Current Hypertension Reviews Peroxisome Proliferator-Activated Receptor (PPAR) in Regenerative Medicine: Molecular Mechanism for PPAR in Stem Cells’ Adipocyte Differentiation
Current Stem Cell Research & Therapy From Physiome to Pathome: A Systems Biology Model of Major Depressive Disorder and the Psycho-Immune-Neuroendocrine Network
Current Psychiatry Reviews Effects of PPARγ Agonists against Vascular and Renal Dysfunction
Current Molecular Pharmacology Editorial (Hot Topic: Coming Back to Nature: Plants as a Vital Source of Pharmaceutically Important Metabolites – Part II A)
Current Medicinal Chemistry First Autochthonous case of Emerged Zoonotic Cutaneous Leishmaniasis in Mazandaran Province, Northern Iran: kDNA-PCR Evidence Base
Infectious Disorders - Drug Targets A Review of Type 2 Diabetes Mellitus Predisposing Genes
Current Diabetes Reviews The Role of Lymphotoxin Receptor Signaling in Diseases
Current Molecular Medicine Prediction of Disease-Related Genes Based on Hybrid Features
Current Proteomics Targeting the Akt Kinase to Modulate Survival, Invasiveness and Drug Resistance of Cancer Cells
Current Medicinal Chemistry Carcinogenesis and Diabetic Wound Healing: Evidences of Parallelism
Current Diabetes Reviews Optimized Soluble Expression and Purification of an Aggregation-prone Protein by Fusion Tag Systems and On-column Cleavage in Escherichia coli
Protein & Peptide Letters