Abstract
Nowadays, the stereoselective synthesis of naturally occurring compounds showing biological activity has attracted much attention and stirred up the interest of organic synthetic chemists. Apparently, the multi-step total synthesis of such complex molecules bearing several stereogenic centers demands the development of the efficient and operational strategies for the induction of chirality in a certain step (steps). Among the most practical approaches in the area of stoichiometric asymmetric synthesis, the SAMP/RAMP hydrazone methodology has been found to be a powerful tool in the synthesis of numerous naturally occurring, and bioactive compounds. In this report, we try to highlight the applications of this methodology in asymmetric synthesis.
In memory of Professor Abbas Shafiee (1937-2016) who trusted me a while ago on a project led to the production of Codeine Phosphate in Iran.Keywords: Chiral auxiliaries, asymmetric synthesis, SAMP/RAMP, stereoselective synthesis.
Current Organic Synthesis
Title:Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis
Volume: 14 Issue: 1
Author(s): Majid M. Heravi, Vahideh Zadsirjan and Mansoureh Daraie
Affiliation:
Keywords: Chiral auxiliaries, asymmetric synthesis, SAMP/RAMP, stereoselective synthesis.
Abstract: Nowadays, the stereoselective synthesis of naturally occurring compounds showing biological activity has attracted much attention and stirred up the interest of organic synthetic chemists. Apparently, the multi-step total synthesis of such complex molecules bearing several stereogenic centers demands the development of the efficient and operational strategies for the induction of chirality in a certain step (steps). Among the most practical approaches in the area of stoichiometric asymmetric synthesis, the SAMP/RAMP hydrazone methodology has been found to be a powerful tool in the synthesis of numerous naturally occurring, and bioactive compounds. In this report, we try to highlight the applications of this methodology in asymmetric synthesis.
In memory of Professor Abbas Shafiee (1937-2016) who trusted me a while ago on a project led to the production of Codeine Phosphate in Iran.Export Options
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Cite this article as:
Heravi M. Majid, Zadsirjan Vahideh and Daraie Mansoureh, Recent Advances in the Applications of SAMP/RAMP as Chiral Auxiliaries in Asymmetric Synthesis, Current Organic Synthesis 2017; 14 (1) . https://dx.doi.org/10.2174/1570179413666160624112433
DOI https://dx.doi.org/10.2174/1570179413666160624112433 |
Print ISSN 1570-1794 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6271 |
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