An Efficient Synthesis of 1,2-Oxazine Derivatives via the Reaction of Acetylenic Esters and 1,2-Diketone Monoxime Derivatives in the Presence of Ph3P

Title:An Efficient Synthesis of 1,2-Oxazine Derivatives via the Reaction of Acetylenic Esters and 1,2-Diketone Monoxime Derivatives in the Presence of Ph3P

Volume: 13 Issue: 6

Author(s): Mitra Saghafi and Razieh Mohebat

Affiliation:

Keywords: 1, 2-Diketone monoxime, Triphenylphosphine, Acetylenic esters, 1, 2-Oxazine, Intramolecular Wittig reaction.

Abstract: The reactive 1:1 intermediate obtained by the addition of triphenylphosphine to dialkyl acetylenedicarboxylates was trapped by 1,2-diketone monoximes to generate functionalized 1,2-oxazine derivatives through intramolecular Wittig reaction without any catalyst in excellent yields.

Cite this article as:

Saghafi Mitra and Mohebat Razieh, An Efficient Synthesis of 1,2-Oxazine Derivatives via the Reaction of Acetylenic Esters and 1,2-Diketone Monoxime Derivatives in the Presence of Ph3P, Letters in Organic Chemistry 2016; 13 (6) . https://dx.doi.org/10.2174/1570178613666160624114703