E-MHK-0103 (Mineraxin™): A Novel Nutraceutical with Biological Properties in Menopausal Conditions

Title:E-MHK-0103 (Mineraxin™): A Novel Nutraceutical with Biological Properties in Menopausal Conditions

Volume: 18 Issue: 1

Author(s): Lola Corzo, Susana Rodriguez, Ramon Alejo, Lucia Fernandez-Novoa, Gjumrakch Aliev and Ramon Cacabelos

Affiliation:

Keywords: Antioxidant capacity, bone stability, iron status, lipoprotein extract, menopause, nutraceutical, osteoporosis, perimenopausal women.

Abstract: Background: Menopause-derived estrogen deprivation and related endocrine factors are linked to some symptoms typical of middle-aged women, such as hot flashes, aches, joint pain, stiffness, depressed mood, bone degeneration, nutritional dysfunction, or difficulty to maintain body mass. Clinical approaches to these problems often involve hormone replacement therapy and other modalities of therapeutic intervention. However, the well-known side effects associated with other pharmacological alternatives have led physicians and patients to pursue new strategies to alleviate these symptoms. As a physiological state, the first recommended option is a natural and healthy therapy, alone or in combination with pharmacotherapy in severe cases. Among other natural alternatives, E-MHK-0103, a nutraceutical lipoprotein extracted from Mytilus galloprovincialis, was found to have beneficial properties.

Methods: We reviewed numerous high-impact references to show the controversies over the current treatments used to alleviate menopausal symptoms, and presented the results obtained with E-MHK-0103 as a good natural alternative.

Results: E-MHK-0103 showed positive effects on hot flashes, mood swings, joint pain and bone stability, associated with its glucosamine-related anti-inflammatory effect and its high content of vitamins, minerals, iron and other substances, such as selenium and vitamin E. A significant increase in serum growth hormone, mediated by the hepatic secretion of insulin growth factor-1, and a slight decrease in bone alkaline phosphatase, calcium and β-crosslaps concentrations contribute to its beneficial impact on bone turnover. E-MHK-0103 also showed a powerful antioxidant effect and an increase in iron stores, of particular importance in women with low basal ferritin levels.

Conclusion: The findings of this review confirm the efficiency of natural therapies in menopause symptoms, and EMHK- 0103 as a healthy choice for inclusion into clinical practice.

Cite this article as:

Corzo Lola, Rodriguez Susana, Alejo Ramon, Fernandez-Novoa Lucia, Aliev Gjumrakch and Cacabelos Ramon, E-MHK-0103 (Mineraxin™): A Novel Nutraceutical with Biological Properties in Menopausal Conditions, Current Drug Metabolism 2017; 18 (1) . https://dx.doi.org/10.2174/1389200217666161014151341

DOI https://dx.doi.org/10.2174/1389200217666161014151341	Print ISSN 1389-2002
Publisher Name Bentham Science Publisher	Online ISSN 1875-5453