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Recent Patents on CNS Drug Discovery
ISSN (Print): 1574-8898
ISSN (Online): 2212-3954
VOLUME: 5
ISSUE: 1
DOI: 10.2174/157488910789753567









New Frontiers in Alcoholism and Addiction Treatment

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Author(s): Felice Nava, Andrea Vendramin, Ezio Manzato, Mauro Cibin and Alfio Lucchini
Pages 81-94 (14)
Abstract:
Drug addiction and alcoholism are behavioural disorders characterized by a profound alteration of several brain circuits induced by chronic drug use. Their treatment is yet based on empiricism and today only few pharmacological strategies are fully effective to control both drug use and relapse. The present paper reviews the most updated pharmacotherapies able to contrast both alcoholism and drug addiction including the new patented drugs and the future therapeutic trends.
Keywords:
Alcoholism, addiction, buprenorphine, methadone, suboxone®, naltrexone, gamma-hydroxybutyrrate, nociceptin peptide receptors, CB1 cannabinoid receptors, dopamine
Affiliation:
Department of Addiction Medicine, Via Ospedale, 18, 31033 Castelfranco Veneto - Treviso, Italy.