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Recent Patents on Inflammation & Allergy Drug Discovery
ISSN (Print): 1872-213X
ISSN (Online): 2212-2710
VOLUME: 1
ISSUE: 1
DOI: 10.2174/187221307779815110









Recent Patents in Pemphigus Research, Prophylaxis, Diagnosis and Treatment in USA (1988-2006)

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Author(s): Daisuke Tsuruta and Hiromi Kobayashi
Pages 77-81 (5)
Abstract:
Pemphigus is an autoimmune blistering disease which is characterized histologically by intraepidermal blisters due to separation of epidermal cell-cell contacts, and immunopathologically by circulating IgG type autoantibodies directed against the desmosomes, which is the cell-cell attachment device in the epidermis. This review briefly summarizes current concepts of conventional diagnosis and treatment of pemphigus, and then focuses on recent US patents related to Pemphigus research, prophylaxis, and diagnosis and treatment from 1988 to 2006. As a result, possible new therapeutic approaches, prophylaxis, diagnostic procedures, or experimental models for the Pemphigus have been disclosed.
Keywords:
Compound, DNA sequence, mapping, plasmapheresis, HLA typing, DELPHION
Affiliation:
Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi, Abeno-ku, Osaka 545-8585 Japan.