Login

Journal Image
Recent Patents on Biotechnology
ISSN (Print): 1872-2083
ISSN (Online): 2212-4012
VOLUME: 3
ISSUE: 1
DOI: 10.2174/187220809787172678









Production and Application of Bacteriophage and Bacteriophage-Encoded Lysins

img
Author(s): Noemie M. Dorval Courchesne, Albert Parisien and Christopher Q. Lan
Pages 37-45 (9)
Abstract:
The widespread resistance to antibiotics among pathogenic bacteria has made development of alternatives to antibiotics a pressing public concern. Extensive studies have established bacteriophages (phages) and phage-encoded lytic enzymes (virolysins) as two of the most promising families of alternative antibacterials for the treatment and prophylaxis of bacterial infections. They have shown great potential in veterinary and human medicine for the treatment and prophylaxis of infections. Technologies have also been patented employing phages and virolysins in other pathogen related applications including detection and decontamination.
Keywords:
Virolysin, antibiotic resistance, lytic enzyme, lysin, bacteriophage
Affiliation:
Department of Chemical and Biological Engineering, The University of Ottawa, Ottawa, ON, K1N 6N5, Canada.