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Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
ISSN (Print): 1872-2148
ISSN (Online): 2212-3334
VOLUME: 3
ISSUE: 3
DOI: 10.2174/187221409789104719









Liraglutide-A Novel GLP-1 Analogue

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Author(s): Sanjay Kalra, Bharti Kalra and Amit Sharma
Pages 200-204 (5)
Abstract:
Liraglutide is a novel glucagon-like peptide 1 analogue, which shows promise as a safe, effective therapy for type 2 diabetes. This review discusses the pathophysiology of type 2 diabetes, focusing on the incretin system, and reviews the pharmacology of liraglutide. A concise discussion of preclinical and clinical data is given, highlighting the benefits of liraglutide with respect to glycaemic control, weight modulation and extraglycaemic effects. This article also review some of recent patents related to the field.
Keywords:
Liraglutide, type 2 diabetes, incretins, glucagon like peptide-1 (GLP-1)
Affiliation:
Bharti Hospital, Kunjpura Road, Karnal, 132001, Haryana, India.