Login

Journal Image
Recent Patents on Drug Delivery & Formulation
ISSN (Print): 1872-2113
ISSN (Online): 2212-4039
VOLUME: 4
ISSUE: 1
DOI: 10.2174/187221110789957264









Properties and Clinical Development of a Novel Coating Technology: The poly[bis(trifluoroethoxy)phosphazene]

img
Author(s): Davide Capodanno and Corrado Tamburino
Pages 18-22 (5)
Abstract:
Ultrapure poly[bis(trifluoroethoxy)phosphazene] is a novel biocompatible, anti-inflammatory, antithrombogenic polymer which has the potential to cover stent devices without elution of a cell cycle inhibiting drug. The properties of polyphosphazene are likely to extend its use to a broad array of promising applications. This article reviews the features of the polymer and some recent patents related to use of poly[bis(trifluoroethoxy)phosphazene] in coating, its relevance as compared to other polymers, current evidence on pre-clinical and clinical performance, and future perspectives.
Keywords:
Polymer, coating, stent
Affiliation:
Cardiology Department, Ferrarotto Hospital, via Citelli 6, 95124 Catania, Italy.