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Current Clinical Pharmacology

Editor-in-Chief

ISSN (Print): 1574-8847
ISSN (Online): 2212-3938

Review Article

Cannabis for Refractory Psoriasis—High Hopes for a Novel Treatment and a Literature Review

Author(s): Nima Derakhshan and Mahboubeh Kazemi

Volume 11 , Issue 2 , 2016

Page: [146 - 147] Pages: 2

DOI: 10.2174/1574884711666160511150126

Price: $65

Abstract

Psoriasis is a common skin disorder characterized by hyper proliferation of keratinocytes. Although the exact pathophysiology of psoriasis is not entirely understood, immune system and its interaction with nervous system have been postulated and investigated as the underlying mechanism. The interaction between these two systems through cholinergic anti-inflammatory pathway and also endocannabinoid system, may suggest cannabinoids as potential addition to antipsoriatic armamentarium.

Keywords: Psoriasis, immunomodulation, cannabidiol, endocannabinoids, vagal nerve stimulation.

Graphical Abstract

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