Abstract
Endometriosis is an inflammatory disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment. The disease affects: ovarian function, oocyte quality, embryo development and implantation, and uterine function resulting in infertility or spontaneous pregnancy loss. Even though the world’s prevalence is above 10 %, an effective treatment has not yet been found. New pharmacological approaches have been designed and patented that could serve as future therapies for this disease.
Keywords: Androgens, coagulation, endometriosis, fertility, GnHR, inflammation, progesterone, signal transduction.
Recent Patents on Endocrine, Metabolic & Immune Drug Discovery
Title:Perspectives of New Therapies for Endometriosis
Volume: 6 Issue: 3
Author(s): Jenny V. Garmendia and Juan B. De Sanctis
Affiliation:
Keywords: Androgens, coagulation, endometriosis, fertility, GnHR, inflammation, progesterone, signal transduction.
Abstract: Endometriosis is an inflammatory disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment. The disease affects: ovarian function, oocyte quality, embryo development and implantation, and uterine function resulting in infertility or spontaneous pregnancy loss. Even though the world’s prevalence is above 10 %, an effective treatment has not yet been found. New pharmacological approaches have been designed and patented that could serve as future therapies for this disease.
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Cite this article as:
V. Garmendia Jenny and B. De Sanctis Juan, Perspectives of New Therapies for Endometriosis, Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 2012; 6 (3) . https://dx.doi.org/10.2174/187221412802481702
DOI https://dx.doi.org/10.2174/187221412802481702 |
Print ISSN 1872-2148 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-3334 |
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