Abstract
NAFLD is the most common liver disease worldwide but it is the potential evolution to cirrhosis and hepatocellular carcinoma (HCC) that makes NAFLD of such clinical importance. The current work provides an overview of the main mechanims and potential therapeutical insights involved in NAFLD, NASH, fibrosis and HCC progression.
Keywords: NAFLD, NASH, fibrosis, microbiota, bacterial translocation.
Current Pharmaceutical Design
Title:From NAFLD to NASH and HCC: Pathogenetic Mechanisms and Therapeutic Insights
Volume: 19 Issue: 29
Author(s): Samuele De Minicis, Chris Day and Gianluca Svegliati-Baroni
Affiliation:
Keywords: NAFLD, NASH, fibrosis, microbiota, bacterial translocation.
Abstract: NAFLD is the most common liver disease worldwide but it is the potential evolution to cirrhosis and hepatocellular carcinoma (HCC) that makes NAFLD of such clinical importance. The current work provides an overview of the main mechanims and potential therapeutical insights involved in NAFLD, NASH, fibrosis and HCC progression.
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De Minicis Samuele, Day Chris and Svegliati-Baroni Gianluca, From NAFLD to NASH and HCC: Pathogenetic Mechanisms and Therapeutic Insights, Current Pharmaceutical Design 2013; 19 (29) . https://dx.doi.org/10.2174/1381612811319290006
DOI https://dx.doi.org/10.2174/1381612811319290006 |
Print ISSN 1381-6128 |
Publisher Name Bentham Science Publisher |
Online ISSN 1873-4286 |
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