Abstract
Calanolides are naturally occurring pyranocoumarins found particularly in Calophyllum species (family Clusiaceae/ Guttiferae), and are well known for their potent anti-human immunodeficiency virus (HIV) activity. Various preclinical and clinical studies with this class of compounds are going on, and the National Cancer Institute (NCI) has been playing an active and supportive role in this regard. The present review covers an up-to-date literature of naturally occurring calanolides in view of their anti-HIV potential and total syntheses including information on related patents.
Keywords: Anti-HIV potential, Calophyllum sp., clusiaceae/guttiferae, natural abundance, natural calanolides, related patents, total syntheses.
Recent Patents on Biotechnology
Title:Naturally Occurring Calanolides: An Update on Their Anti-HIV Potential and Total Syntheses
Volume: 8 Issue: 1
Author(s): Goutam Brahmachari and Shyamal K. Jash
Affiliation:
Keywords: Anti-HIV potential, Calophyllum sp., clusiaceae/guttiferae, natural abundance, natural calanolides, related patents, total syntheses.
Abstract: Calanolides are naturally occurring pyranocoumarins found particularly in Calophyllum species (family Clusiaceae/ Guttiferae), and are well known for their potent anti-human immunodeficiency virus (HIV) activity. Various preclinical and clinical studies with this class of compounds are going on, and the National Cancer Institute (NCI) has been playing an active and supportive role in this regard. The present review covers an up-to-date literature of naturally occurring calanolides in view of their anti-HIV potential and total syntheses including information on related patents.
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Cite this article as:
Brahmachari Goutam and Jash K. Shyamal, Naturally Occurring Calanolides: An Update on Their Anti-HIV Potential and Total Syntheses, Recent Patents on Biotechnology 2014; 8 (1) . https://dx.doi.org/10.2174/1872208307666131218123753
DOI https://dx.doi.org/10.2174/1872208307666131218123753 |
Print ISSN 1872-2083 |
Publisher Name Bentham Science Publisher |
Online ISSN 2212-4012 |
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