Abstract
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that control essential cellular activities. Many viruses use these regulators to help infect host cells and maintain their presence in those cells. Therefore, virus-encoded miRNAs are important tools for viruses in the battle with their hosts. Knowledge of these miRNAs is essential for the development of new drugs to treat viral diseases and virus-associated cancers. In this minireview, the miRNAs encoded in viral genomes, their expression and functions, the interactions between viral and cellular miRNAs in viral diseases and virus- associated cancers, and the use of miRNAs for therapy are described.
Keywords: Cellular miRNA, expression, interaction, latent infection, lytic infection, viral miRNA, viruses.
MicroRNA
Title:MicroRNAs in Human Virus Genomes: Helping Hands for Viral Infection
Volume: 3 Issue: 2
Author(s): Ding-Gan Liu
Affiliation:
Keywords: Cellular miRNA, expression, interaction, latent infection, lytic infection, viral miRNA, viruses.
Abstract: MicroRNAs (miRNAs) are small noncoding regulatory RNAs that control essential cellular activities. Many viruses use these regulators to help infect host cells and maintain their presence in those cells. Therefore, virus-encoded miRNAs are important tools for viruses in the battle with their hosts. Knowledge of these miRNAs is essential for the development of new drugs to treat viral diseases and virus-associated cancers. In this minireview, the miRNAs encoded in viral genomes, their expression and functions, the interactions between viral and cellular miRNAs in viral diseases and virus- associated cancers, and the use of miRNAs for therapy are described.
Export Options
About this article
Cite this article as:
Liu Ding-Gan, MicroRNAs in Human Virus Genomes: Helping Hands for Viral Infection, MicroRNA 2014; 3 (2) . https://dx.doi.org/10.2174/2211536603666140825193447
DOI https://dx.doi.org/10.2174/2211536603666140825193447 |
Print ISSN 2211-5366 |
Publisher Name Bentham Science Publisher |
Online ISSN 2211-5374 |
Call for Papers in Thematic Issues
Modulatory Roles of Non-coding RNAs in cancer therapy
This thematic issue aims to elucidate the most recent research on ncRNAs in CRCs and discuss the importance and difficulties that may arise in applying this tool on a regular clinical basis.read more
Related Journals
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Hypermethylation of Single CpG Dinucleotides at the Promoter of CXCL13 Gene Promoting Cell Migration in Cervical Cancer
Current Cancer Drug Targets Multifaceted Role of Neuropilins in Cancer
Current Medicinal Chemistry Pharmacological Inhibition of Poly(ADP-ribose) Polymerase (PARP) Activity in PARP-1 Silenced Tumour Cells Increases Chemosensitivity to Temozolomide and to a N3-Adenine Selective Methylating Agent
Current Cancer Drug Targets PET/CT Based Dose Planning in Radiotherapy
Current Medical Imaging To Die or Not to Die: That is the Autophagic Question
Current Molecular Medicine Ascorbic Acid in Cancer Chemoprevention: Translational Perspectives and Efficacy
Current Drug Targets Terpyridines and their Complexes with First Row Transition Metal Ions:Cytotoxicity, Nuclease Activity and Self-Assembly of Biomacromolecules
Current Topics in Medicinal Chemistry Carbon Nanotubes: An Emerging Drug Delivery Carrier in Cancer Therapeutics
Current Drug Delivery PI3K/AKT/mTOR Inhibitors In Ovarian Cancer
Current Medicinal Chemistry Thioredoxin and Thioredoxin Reductase As Redox-Sensitive Molecular Targets for Cancer Therapy
Current Pharmaceutical Design Prostate Cancer Prevention in the Developing World - What are we Waiting for?
Current Pharmacogenomics and Personalized Medicine Drug Delivery Approaches for Doxorubicin in the Management of Cancers
Current Cancer Therapy Reviews Resisting the Resistance in Cancer: Cheminformatics Studies on Short- Path Base Excision Repair Pathway Antagonists Using Supervised Learning Approaches
Combinatorial Chemistry & High Throughput Screening Correlation of Fixed Aqueous Layer Thickness Around PEG-modified Liposomes with In Vivo Efficacy of Antitumor Agent-containing Liposomes
Current Drug Discovery Technologies Artemisia Species as a New Candidate for Diabetes Therapy: A Comprehensive Review
Current Molecular Medicine Gambogic Acid is a Novel Anti-cancer Agent that Inhibits Cell Proliferation, Angiogenesis and Metastasis
Anti-Cancer Agents in Medicinal Chemistry Cervical Cancer: Will Interventions to HPV Vaccination Reduce Disparities?
Current Women`s Health Reviews Immunotherapeutic Options for Pediatric Malignancies
Current Immunology Reviews (Discontinued) <I>In-silico</I> Molecular Interaction of Short Synthetic Lipopeptide/Importin-alpha and <I>In-vitro</I> Evaluation of Transgene Expression Mediated by Liposome- Based Gene Carrier
Current Gene Therapy Promotion of Cortico-Cerebral Precursors Expansion by Artificial pri-miRNAs Targeted Against the Emx2 Locus
Current Gene Therapy