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Anti-Cancer Agents in Medicinal Chemistry

Editor-in-Chief

ISSN (Print): 1871-5206
ISSN (Online): 1875-5992

Review of Procedures Used for the Extraction of Anti-Cancer Compounds from Tropical Plants

Author(s): Saurabh Pandey, Paul N. Shaw and Amitha K. Hewavitharana

Volume 15, Issue 3, 2015

Page: [314 - 326] Pages: 13

DOI: 10.2174/1871520614666141114202104

Price: $65

Abstract

Tropical plants are important sources of anti-cancer lead molecules. According to the US National Cancer Institute, out of the 3000 plants identified as active against cancer using in vitro studies, 70% are of tropical origin. The extraction of bioactive compounds from the plant materials is a fundamental step whose efficiency is critical for the success of drug discovery efforts. There has been no review published of the extraction procedures of anti-cancer compounds from tropical plants and hence the following is a critical evaluation of such procedures undertaken prior to the use of these compounds in cancer cell line studies, during the last five years. It presents a comprehensive analysis of all approaches taken to extract anti-cancer compounds from various tropical plants. (Databases searched were PubMed, SciFinder, Web of Knowledge, Scopus, Embase and Google Scholar).

Keywords: Anti-cancer, bio actives, drug discovery, extraction, tropical plants.

Graphical Abstract

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