Abstract
Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.
Keywords: Agents, antimicrobial, antitumoral, synthesis, organotin(IV).
Mini-Reviews in Medicinal Chemistry
Title:Synthesis and Biological Activities of Organotin(IV) Complexes as Antitumoral and Antimicrobial Agents. A Review
Volume: 15 Issue: 5
Author(s): Syed Shoaib Ahmad Shah, Muhammad Ashfaq, Amir Waseem, M. Mehboob Ahmed, Tayyaba Najam, Salma Shaheen and Gildardo Rivera
Affiliation:
Keywords: Agents, antimicrobial, antitumoral, synthesis, organotin(IV).
Abstract: Advances in the use of organotin(IV) compounds have gained relevant interest in both the chemical and pharmaceutical industry. Tin(IV) form stable complexes with a unique structure and physicochemical properties that are used in organic synthesis as heat stabilizers and catalysts, in drug development as biologically active agents, and in other areas. This review focuses on recent progress in the classical and convenient synthesis procedure, on their mechanism of action, and biological activities as antitumoral and antimicrobial agents.
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Cite this article as:
Shah Shoaib Ahmad Syed, Ashfaq Muhammad, Waseem Amir, Ahmed Mehboob M., Najam Tayyaba, Shaheen Salma and Rivera Gildardo, Synthesis and Biological Activities of Organotin(IV) Complexes as Antitumoral and Antimicrobial Agents. A Review, Mini-Reviews in Medicinal Chemistry 2015; 15 (5) . https://dx.doi.org/10.2174/138955751505150408142958
DOI https://dx.doi.org/10.2174/138955751505150408142958 |
Print ISSN 1389-5575 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-5607 |
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