Abstract
The surgical treatment of tetralogy of Fallot can be considered as a success story in the history of congenital heart diseases. Since the early outcome is no longer the main issue, the focus moved to the late sequelae of TOF repair, i.e. the pulmonary insufficiency and the secondary adaptation of the right ventricle. This review provides recent insights into the pathophysiological alterations of the right ventricle in relation to the reconstruction of the right ventricular outflow tract after repair of tetralogy of Fallot. Its clinical relevance is documented by addressing the policy changes regarding the optimal management at the time of surgical repair as well as properly defining criteria and timing for late pulmonary valve implantation.
Keywords: Pulmonary regurgitation, right ventricle physiology, surgery, tetralogy of fallot.
Current Pediatric Reviews
Title:New Insights into the Surgical Management of Tetralogy of Fallot: Physiological Fundamentals and Clinical Relevance
Volume: 11 Issue: 2
Author(s): Thierry Bove, Katrien Francois and Daniel De Wolf
Affiliation:
Keywords: Pulmonary regurgitation, right ventricle physiology, surgery, tetralogy of fallot.
Abstract: The surgical treatment of tetralogy of Fallot can be considered as a success story in the history of congenital heart diseases. Since the early outcome is no longer the main issue, the focus moved to the late sequelae of TOF repair, i.e. the pulmonary insufficiency and the secondary adaptation of the right ventricle. This review provides recent insights into the pathophysiological alterations of the right ventricle in relation to the reconstruction of the right ventricular outflow tract after repair of tetralogy of Fallot. Its clinical relevance is documented by addressing the policy changes regarding the optimal management at the time of surgical repair as well as properly defining criteria and timing for late pulmonary valve implantation.
Export Options
About this article
Cite this article as:
Bove Thierry, Francois Katrien and Wolf De Daniel, New Insights into the Surgical Management of Tetralogy of Fallot: Physiological Fundamentals and Clinical Relevance, Current Pediatric Reviews 2015; 11 (2) . https://dx.doi.org/10.2174/1573396311666150702103756
DOI https://dx.doi.org/10.2174/1573396311666150702103756 |
Print ISSN 1573-3963 |
Publisher Name Bentham Science Publisher |
Online ISSN 1875-6336 |
- Author Guidelines
- Graphical Abstracts
- Fabricating and Stating False Information
- Research Misconduct
- Post Publication Discussions and Corrections
- Publishing Ethics and Rectitude
- Increase Visibility of Your Article
- Archiving Policies
- Peer Review Workflow
- Order Your Article Before Print
- Promote Your Article
- Manuscript Transfer Facility
- Editorial Policies
- Allegations from Whistleblowers
Related Articles
-
Neurocognitive Monitoring and Care During Pediatric Cardiopulmonary Bypass — Current and Future Directions
Current Cardiology Reviews The Spatial QRS-T Angle: Implications in Clinical Practice
Current Cardiology Reviews Impact of Pulmonary Vascular Resistances in Heart Transplantation for Congenital Heart Disease
Current Cardiology Reviews Therapeutic Potential of N-Acetylcysteine for Wound Healing, Acute Bronchiolitis, and Congenital Heart Defects
Current Drug Metabolism Noncardiac Surgery: Evaluating and Minimizing Cardiac Risk
Current Cardiology Reviews Economic Evaluation in Paediatric Practice: Examples from Cardiac Critical Care
Current Pediatric Reviews Value of Abnormal Fetal Cardiac Axis in the Fetal Congenital Heart Disease
Current Medical Imaging Propranolol Safety Profile in Children
Current Drug Safety Large Unrepaired Aortopulmonary Window Presenting in Adulthood
Current Cardiology Reviews Role of Genetic Factors in the Pathogenesis of Radial Deficiencies in Humans
Current Genomics A Comparative Effectiveness Systematic Review and Meta-analysis of Drugs for the Prophylaxis of Junctional Ectopic Tachycardia
Current Cardiology Reviews Cardiac Chamber Volumetric Assessment Using 3D Ultrasound - A Review
Current Pharmaceutical Design Prediction of Tetralogy of Fallot using Fuzzy Clustering
Recent Advances in Computer Science and Communications Editorial (Thematic Issue: Cardiovascular Drug Therapy in Paediatric Age: From Metabolomics to Clinical Practice)
Current Medicinal Chemistry Predictors of Ominous Outcome in Infants who Undergo Cardiac Surgery and Cardiopulmonary By-Pass: S100B Protein
CNS & Neurological Disorders - Drug Targets Variations and Abnormalities of Major Thoracic Vascular Structures
Current Medical Imaging Effects of Maternal Obesity on Maternal and Fetal Health
Current Women`s Health Reviews Cardiovascular Complications in Patients with Klinefelter’s Syndrome
Current Pharmaceutical Design Clinical and Genetic Features of Warts, Hypogammaglobulinemia, Infections and Myelokathexis (WHIM) Syndrome
Current Molecular Medicine The Secondary Heart Field: Understanding Conotruncal Defects from a Developmental Perspective
Current Cardiology Reviews