Abstract
In the article authors discuss the current data on sleep changes with aging focusing on the influence of age-related degenerative changes in orexin-containing and pacemaker brain areas. Pathophysiological mechanisms of sleep disturbances in Parkinson’s and Alzheimer’s diseases have much in common with normal age neurophysiological changes. Maintenance of the sleep-promoting systems function could positively modify the course of these diseases.
Keywords: Age, Alzheimer’s disease, Parkinson’s disease, sleep, orexins, sleep disorders.
Current Aging Science
Title:Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases
Volume: 9 Issue: 1
Author(s): Elena A. Lyashenko, Michael G. Poluektov, Oleg S. Levin and Polina V. Pchelina
Affiliation:
Keywords: Age, Alzheimer’s disease, Parkinson’s disease, sleep, orexins, sleep disorders.
Abstract: In the article authors discuss the current data on sleep changes with aging focusing on the influence of age-related degenerative changes in orexin-containing and pacemaker brain areas. Pathophysiological mechanisms of sleep disturbances in Parkinson’s and Alzheimer’s diseases have much in common with normal age neurophysiological changes. Maintenance of the sleep-promoting systems function could positively modify the course of these diseases.
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Cite this article as:
A. Lyashenko Elena, G. Poluektov Michael, S. Levin Oleg and V. Pchelina Polina, Age-Related Sleep Changes and its Implication in Neurodegenerative Diseases, Current Aging Science 2016; 9 (1) . https://dx.doi.org/10.2174/1874609809666151130220219
DOI https://dx.doi.org/10.2174/1874609809666151130220219 |
Print ISSN 1874-6098 |
Publisher Name Bentham Science Publisher |
Online ISSN 1874-6128 |
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